Lipomatous tumors
Table of Contents

Liposarcoma

Epidemiology

  • second most common soft tissue sarcoma
  • 40% (most common) - myxoid liposarcoma (mostly low-grade/intermediate-grade)

Clinical

  • Most commonly presents in the lower extremities followed by the retroperitoneum/intra-abdominal areas.

Recurrence

  • myxoid liposarcoma has unusual pattern of recurrence
    • predilection for soft tissue metastasis, most commonly retroperitoneum and mediastinum
    • multifocal recurrence pattern

Treatment

  • myxoid liposarcoma has unusual sensitive response to RT
  • marginal or intralesional resection and RT (median 60 Gy) "high" 5-year local control rate.[1]
Bibliography
1. Hatano H, Ogose A, Hotta T, Kawashima H, Sugita T, Sasamoto R, Endo N. Treatment of myxoid liposarcoma by marginal or intralesional resection combined with radiotherapy. Anticancer Res. 2003 May-Jun;23(3C):3045-9. PMID: 12926159
Unless otherwise stated, the content of this page is licensed under Creative Commons Attribution-Share Alike 2.5 License.