Infected PEG tube site

Although enteral tube-site infections are often polymicrobial, Staphylococcus aureus and beta-hemolytic streptococci are commonly involved organisms. In addition, fungal superinfection is not uncommon. Unless a specific organism is identified by means of cultures, the first-line therapy should be directed toward common bacterial organisms. First-line oral antibiotics include Keflex (cephalexin 250-1000 mg by mouth [PO] q6h) and Augmentin (amoxicillin/clavulanate 500-875 mg PO q12h). In patients with anaphylactic reactions to penicillin, Cleocin (clindamycin 150-450 mg PO q6h) should be considered.

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