DVH Considerations for GI Tumors

Small Bowel

RT with 5-FU

  • keeping the small bowel volume receiving more than 15 Gy under 150 cc.[1]

Grade 3 Diarrhea vs Dose in 5FU + RT Patients[2]

  • high-risk patients (31%) are above the line
  • low-risk patients (9%) are below the line
1. Gunnlaugsson A, Kjellén E, Nilsson P, Bendahl PO, Willner J, Johnsson A.Dose-volume relationships between enteritis and irradiated bowel volumes during 5-fluorouracil and oxaliplatin based chemoradiotherapy in locally advanced rectal cancer.Acta Oncol. 2007;46(7):937-44.
2. John M. Robertson, David Lockman, Di Yan, Michelle Wallace. The Dose–Volume Relationship of Small Bowel Irradiation and Acute Grade 3 Diarrhea During Chemoradiotherapy for Rectal Cancer. International Journal of Radiation Oncology * Biology * Physics 1 February 2008 (Vol. 70, Issue 2, Pages 413-418)
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