Breast Partial

5-year results of Randomized trial.[1]
Local Recurrence

  • PBI 4.7%
  • WBI 3.4%
  • p = 0.50.

Overall Survival

  • PBI (94.6%)
  • WBI (91.8%)
  • p = NS.

The rate of excellent to good cosmetic result:

  • PBI 77.6%
    • HDR PBI 81.2%
    • EB PBI 70.0%
  • WBI 62.9%
    • telecobalt 52.2%
    • 6-9-MV photons 65.9%
  • p(WBI/PBI) = 0.009.

Fat Necrosis Rate at 4 years[2]

  • WBI 31.9%
  • HDR-BT 36.5%
  • ELE 17.7%
  • p(WBI/HDR-BT) = 0.26; p(WBI/ELE) = 0.11; p(ELE/HDR-BT) = 0.025

Notation

partial-breast irradiation (PBI)
interstitial high-dose-rate brachytherapy (HDR-BT)
partial-breast electron irradiation (ELE)

Bibliography
1. Polgár C, Fodor J, Major T, Németh G, Lövey K, Orosz Z, Sulyok Z, Takácsi-Nagy Z, Kásler M. Breast-conserving treatment with partial or whole breast irradiation for low-risk invasive breast carcinoma 5-year results of a randomized trial. Int J Radiat Oncol Biol Phys. 2007 Nov 1;69(3): 694-702.
2. Lövey K, Fodor J, Major T, Szabó E, Orosz Z, Sulyok Z, Jánváry L, Fröhlich G, Kásler M, Polgár C. Fat necrosis after partial-breast irradiation with brachytherapy or electron irradiation versus standard whole-breast radiotherapy—4-year results of a randomized trial. Int J Radiat Oncol Biol Phys. 2007 Nov 1;69(3): 724-31.
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